Anopheles gambiae (Anopheles gambiae)

Anopheles gambiae is the primary mosquito vector responsible for the transmission of malaria in Sub-Saharan Africa.

Assembly

The genome assembly presented here (AgamP3, February 2006) is a revised assembly based on the whole genome shotgun assembly of the PEST strain of Anopheles gambiae produced by the The International Anopheles Genome Project and described in Holt et al (October 2002) with revisions as described in Sharakhova et al (2007).

Annotation

Annotation of the AgamP3 assembly was carried out by VectorBase. The set of gene models presented (genebuild AgamP3.5, released September 2009) combines manual annotation of chromosome arm 2L,2R & X, data provided by the research community, and gene prediction using the Ensembl system. Prediction utilised alignments of dipteran and other protein sets to the genome and generation of GeneWise models, alignment and gene prediction based on Anopheles ESTs, and selected ab initio predictions. 'Known' genes are those which could be named using entries from the community gene symbol database or from UniProt.

Genome Statistics