Bioinformatics Resource for Invertebrate Vectors of Human Pathogens
All Experiments
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Gene expression in Aedes aegypti was compared between a Wolbachia infected strain and an uninfected strain (tetracycline treated 40 generations prior). A full genome (AaegL1.1) 60-mer Agilent custom-commercial microarray was used. 
A whole-genome custom microarray was used to assay gene expression changes in Aedes aegypti in response to a blood meal over a period of several days. This dataset can also be queried at http://www.aegep.bio.uci.edu/ or downloaded from GEO
A whole-genome custom microarray was used to assay gene expression differences between male and female adult Aedes aegypti. This dataset can also be queried at http://www.aegep.bio.uci.edu/ or downloaded from GEO
A pyrethroid-resistant strain of Culex quinquefasciatus, JPal-per, exhibits 2500-fold greater larval resistance to permethrin than the insecticide-susceptible strain Ogasawara. Here, a custom microarray analysis has assayed the relative levels of 62 cytochrome P450 genes (and a few non P450 genes) between these two strains. GEO: GSE17326
Gene expression differences between a pyrethroid resistant strain (FUMOZ-R) of Anopheles funestus from Mozambique and a susceptible strain (FANG) of the same species from Angola were measured using the "Detox" chip designed for Anopheles gambiae, which features mostly detoxification genes. Adult females and males have been assayed separately. DOI link to publication (no PubMed ID available) 
Anopheles gambiae larvae with or without the 2La chromosomal inversion were assayed for gene expression differences in the presence or absence of thermal stress at three time points. 
Gene expression in larvae and adults of the Imida-R imidacloprid insecticide resistant strain of Aedes aegypti is compared with expression in a susceptible strain, Bora-Bora, using an Agilent technologies microarray with 60mer probes targeting 14192 genes. 
Gene expression in laboratory-selected permethrin resistant Aedes aegypti larvae is compared to that of susceptible Bora-Bora strain larvae, using an Agilent technologies microarray with 60mer probes targeting 14192 genes. Two of the three sub-experiments involve exposure of the larvae to sub-lethal amounts of fluoranthene (100 µg/L) and permethrin (0.4 µg/L) during rounds of selection. 
factor:
OrganismPart:Sex
 
This is the MozAtlas dataset. A number of tissues dissected from adult male and female Anopheles gambiae mosquitoes are assayed on the Affymetrix Plasmodium/Anopheles microarray. GEO: GSE21689 
A custom Agilent microarray was used to examine global gene expression during the adult lifetime of male Anopheles gambiae mosquitoes; more specifically at 10 day intervals post eclosion. GEO: GSE18194 
A custom Agilent microarray was used to examine global gene expression during the adult lifetime of female Anopheles gambiae mosquitoes; more specifically at 10 day intervals post eclosion. GEO: GSE18194 
factor:
DiseaseState
DiseaseStaging
DiseaseState:DiseaseStaging
 
The transcriptional response of Anopheles gambiae to varying Plasmodium falciparum infection intensities was measured at three time-points. The parasite strains were obtained from asymptomatic carriers in Cameroon. Local mosquitoes were used to create the laboratory colony. 
factor:
DiseaseState
DiseaseStaging
DiseaseState:DiseaseStaging
 
The transcriptional response of Anopheles gambiae to varying Plasmodium berghei (rodent malaria parasite) infection intensities was measured at three time-points. 
factor:
DevelopmentalStage:Age:Sex
 
Transgenic G3 strain Anopheles gambiae mosquitoes expressing a GFP construct were sexed at early larval stage. Female vs. male expression ratios were assayed at three larval stages and in pupae and adults. 
A laboratory strain of Aedes aegypti was selected for resistance to Bacillus thuringiensis var. israelensis (Bti), a larval pathogen, by exposure to its toxins during 30 generations. Gene expression in midguts is compared between the resistant strain, LiTOX, and the control Bora-Bora strain. 
factor:
GrowthCondition
 
Gene expression in Anopheles gambiae G3 strain mosquitoes exposed to moderate and extreme desiccating conditions (70% and 30% RH respectively) was assayed on the Affymetrix platform. GEO: GSE25433 
Anopheles gambiae S form adults were drawn from the GAH laboratory colony that originated from the Ahafo region in Ghana. The GAH colony exhibits extensive insecticide resistance (bendiocarb, DDT, dieldrin, permethrin, deltamethrin). Gene expression was compared between blood-fed and sugar-fed females (3 hours after feeding) using a custom array focussing on around 300 detoxification-related genes. 
Gene expression was compared between Plasmodium berghei-infected and uninfected adult female Anopheles gambiae mosquitoes at 10 and 17 days post infection. NCBI GEO: GSE32200
Wolbachia is a vertically transmitted intracellular bacterium that infects more than 60% of insect species. However, it does not naturally infect Aedes aegypti. The Wolbachia strains wMelPop and wMel were introduced into laboratory strains of Aedes aegypti mosquitoes and gene expression was compared between these Wolbachia infected strains and their tetracyclin antibiotic cleared counterparts. ArrayExpress: E-MEXP-2931 
factor:
DiseaseState:OrganismPart
 
The Wolbachia strain wMelPop, which reduces longevity in Drosophila melanogaster, has been introduced into the Dengue virus mosquito vector, Aedes aegypti, as a strategy to reduce disease transmission. In this experiment, gene expression is compared between Wolbachia infected and uninfected mosquito tissues: head and muscle. ArrayExpress: E-MEXP-2907 
133 items found, displaying 41 to 60.[First/Prev] 1, 2, 3, 4, 5, 6, 7 [Next/Last]