Bioinformatics Resource for Invertebrate Vectors of Human Pathogens
Gene AGAP001111 Expression Report
Gene links
Anopheles gambiae

Probe Information show details
Expression summary
Experiment P-value Test Experimental factor Summary
Adult tissues (Baker et al., 2011)
Microarray experiment info
Plots and data
0.0
ANOVA
Organism part and sex
Significant differential expression
↑ Malpighian tubules:male
↓ male accessory gland:male
MR4 cell-lines (AVCL consortium, 2014)
RNA-Seq experiment info
Plots and data
4.4e-12
ANOVA
Strain or line
Significant differential expression
↑ MRA-920 L35
↓ MRA-918 4a-3A
Blood meal time series (Marinotti et al., 2006)
Microarray experiment info
Plots and data
3.8e-09
ANOVA
Growth condition
Significant differential expression
↑ blood-fed 15d
↓ blood_fed 72h
Click here for more results from Blood meal time series (Marinotti et al., 2006)
Embryonic development (Goltsev et al., 2009)
Microarray experiment info
Plots and data
3.7e-08
ANOVA
Age
Significant differential expression
↑ 43h
↓ 7h
Click here for more results from Embryonic development (Goltsev et al., 2009)
Female lower reproductive tract post-mating time-series (Gabrieli et al., 2014)
Microarray experiment info
Plots and data
2.1e-07
ANOVA
Developmental stage
Significant differential expression
↑ virgin adult
↓ mated adult
Click here for more results from Female lower reproductive tract post-mating time-series (Gabrieli et al., 2014)
Alimentary canal compartments (Neira Oviedo et al., 2008)
Microarray experiment info
Plots and data
2.7e-06
ANOVA
Organism part
Significant differential expression
↑ hindgut
↓ anterior midgut
Blood-fed adult female tissues (Marinotti et al., 2006)
Microarray experiment info
Plots and data
4.6e-06
ANOVA
Organism part
Significant differential expression
↑ midgut
↓ ovaries
Sua5B cell-line infected vs uninfected (AVCL consortium, 2014)
RNA-Seq experiment info
Plots and data
1.5e-05
ANOVA
Disease state
Significant differential expression
↑ wMel infected
↓ wAlB infected
Hemolymph, carcass and head (Pinto et al., 2009)
Microarray experiment info
Plots and data
2.1e-05
ANOVA
Organism part
Significant differential expression
↑ head
↓ hemolymph
Two consecutive blood meals (Marinotti et al., 2006)
Microarray experiment info
Plots and data
0.00034
ANOVA
Growth condition
Significant differential expression
↑ Non-blood-fed
↓ blood-fed twice
Click here for more results from Two consecutive blood meals (Marinotti et al., 2006)
Desiccation stress (Wang et al., 2011)
Microarray experiment info
Plots and data
0.00044
ANOVA
Growth condition
Significant differential expression
↑ Exposed to 70% RH 36hr
↓ Exposed to 30% RH 36hr
Response to thermal stress in 2La and 2L+(a) karyotype mosquitoes (Cassone et al., 2011)
Microarray experiment info
Plots and data
0.00059
ANOVA
Genotype and growth condition and time
Significant differential expression
↑ 2La standard:control:8.0 h
↓ 2La inverted:control:2.0 h
M and S form gravid females (Cassone et al., 2008)
Microarray experiment info
Plots and data
0.00076
ANOVA
Genotype and strain or line
Significant differential expression
↑ S form:Pimperena
↓ S form:KIST
Click here for more results from M and S form gravid females (Cassone et al., 2008)
Sex-biased expression in gambiae (Papa et al., 2017)
RNA-Seq experiment info
Plots and data
0.0014
ANOVA
Organism part and sex
Significant differential expression
↑ reproductive tissues:male
↓ reproductive tissues:female
Circadian rhythm: heads, dark-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
0.0045
ANOVA
Time
Significant differential expression
↑ 8.0 h
↓ 48.0 h
Female lower reproductive tract 20E injection (Gabrieli et al., 2014)
Microarray experiment info
Plots and data
0.0052
t-test
Compound and organism part
Significant 1.3-fold down-regulation with respect to
20-hydroxyecdysone v 10% Ethanol:Atrium
Click here for more results from Female lower reproductive tract 20E injection (Gabrieli et al., 2014)
Larval and adult stages (Marinotti et al., 2006)
Microarray experiment info
Plots and data
0.0059
ANOVA
Developmental stage
Significant differential expression
↑ adult
↓ larva
Plasmodium berghei infections (Mendes et al., 2011)
Microarray experiment info
Plots and data
0.0072
t-test
Disease state
Significant 1.5-fold up-regulation with respect to
high-intensity Plasmodium berghei infected v heat-inactivated mock infected
Click here for more results from Plasmodium berghei infections (Mendes et al., 2011)
M and S form virgin females (Cassone et al., 2008)
Microarray experiment info
Plots and data
0.0074
ANOVA
Genotype and strain or line
Significant differential expression
↑ M form:M-GA-CAM
↓ M form:Mali-NIH
Click here for more results from M and S form virgin females (Cassone et al., 2008)
Sex-bias during development (Magnusson et al., 2011)
Microarray experiment info
Plots and data
0.018
Neighbour t-test
Developmental stage and age and sex
Significant 3.4-fold upward change between:
← pupa:216 hours:female v male
→ adult:312 hours:female v male
Click here for more results from Sex-bias during development (Magnusson et al., 2011)
Plasmodium berghei infected vs. uninfected (Zhao et al., 2012)
Microarray experiment info
Plots and data
0.018
Neighbour t-test
Disease state and disease staging
Significant 1.2-fold downward change between:
← P. berghei NK65 infected v uninfected:10 days post infection
→ P. berghei NK65 infected v uninfected:17 days post infection
Click here for more results from Plasmodium berghei infected vs. uninfected (Zhao et al., 2012)
Mated vs virgin spermatheca (Shaw et al., 2014)
Microarray experiment info
Plots and data
0.020
t-test
Developmental stage
Significant 1.6-fold down-regulation with respect to
mated adult v virgin adult
Developmental series (Koutsos et al., 2007)
Microarray experiment info
Plots and data
0.021
ANOVA
Developmental stage and age
Significant differential expression
↑ larva:48 hours
↓ embryo:12-14 hours
Click here for more results from Developmental series (Koutsos et al., 2007)
Circadian rhythm: heads, light-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
0.15
ANOVA
Time
Non-significant differential expression
↑ 36.0 h
↓ 44.0 h
Transcript abundance after bloodmeal (Vannini et al., 2014)
RNA-Seq experiment info
Plots and data
0.17
ANOVA
Growth condition
Non-significant differential expression
↑ Non-blood-fed
↓ blood-fed
Chloroquine exposure (Abrantes et al., 2008)
Microarray experiment info
Plots and data
0.18
t-test
Compound and disease state
Non-significant 1.4-fold up-regulation with respect to
chloroquine v none:uninfected
Click here for more results from Chloroquine exposure (Abrantes et al., 2008)
Hemocyte response to Plasmodium berghei infection (Pinto et al., 2009)
Microarray experiment info
Plots and data
0.18
Neighbour t-test
Disease state
Non-significant 1.1-fold upward change between:
← invasion-deficient parasite infection
→ wild-type parasite infection
Mated females (Rogers et al., 2009)
Microarray experiment info
Plots and data
0.19
Neighbour t-test
Growth condition
Non-significant 1.2-fold downward change between:
← virgin 0h
→ mated 2h
Click here for more results from Mated females (Rogers et al., 2009)
Translational regulation in the midgut during falciparum infection (Mead et al., 2012)
RNA-Seq experiment info
Plots and data
0.19
ANOVA
Material type and disease state
Non-significant differential expression
↑ total RNA:infection with P. falciparum 3D7G
↓ polysome associated RNA:uninfected control
Adult male mosquito ageing (Cook & Sinkins, 2010)
Microarray experiment info
Plots and data
0.20
ANOVA
Age
Non-significant differential expression
↑ 10 days
↓ 0 days
Click here for more results from Adult male mosquito ageing (Cook & Sinkins, 2010)
Plasmodium falciparum infections (Mendes et al., 2011)
Microarray experiment info
Plots and data
0.20
t-test
Disease staging
Non-significant 1.2-fold up-regulation with respect to
before midgut invasion
Click here for more results from Plasmodium falciparum infections (Mendes et al., 2011)
Circadian rhythm: bodies, dark-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
0.20
ANOVA
Time
Non-significant differential expression
↑ 0.0 h
↓ 4.0 h
Adult female mosquito ageing (Cook & Sinkins, 2010)
Microarray experiment info
Plots and data
0.21
Neighbour t-test
Age
Non-significant 1.3-fold downward change between:
← 20 days
→ 30 days
Click here for more results from Adult female mosquito ageing (Cook & Sinkins, 2010)
Blood meal after 15 days (Marinotti et al., 2006)
Microarray experiment info
Plots and data
0.22
ANOVA
Growth condition
Non-significant differential expression
↑ blood-fed 15d
↓ Non-blood-fed 18d
Modulation of blood seeking, feeding & susceptibility to infection (Emami et al., 2017)
RNA-Seq experiment info
Plots and data
0.26
ANOVA
Growth condition and time
Non-significant differential expression
↑ blood-fed:6.0 h
↓ blood-fed:3.0 h
MOS55 cell-line infected vs uninfected (AVCL consortium, 2014)
RNA-Seq experiment info
Plots and data
0.28
ANOVA
Disease state
Non-significant differential expression
↑ Uninfected
↓ wMelPop infected
Male vs. female (Koutsos et al., 2007)
Microarray experiment info
Plots and data
0.32
ANOVA
Sex
Non-significant differential expression
↑ male
↓ female
M and S form 4th instar larvae (Cassone et al., 2008)
Microarray experiment info
Plots and data
0.32
ANOVA
Genotype and strain or line
Non-significant differential expression
↑ M form:Mali-NIH
↓ M form:M-GA-CAM
Click here for more results from M and S form 4th instar larvae (Cassone et al., 2008)
Male vs. female (Marinotti et al., 2006)
Microarray experiment info
Plots and data
0.60
ANOVA
Sex
Non-significant differential expression
↑ male
↓ female
Plasmodium berghei midgut invasion stage comparisons (Vlachou et al., 2005)
Microarray experiment info
Plots and data
0.62
t-test
Disease state and disease staging
Non-significant 1.1-fold down-regulation with respect to
wild-type parasite infection:after midgut invasion v during midgut invasion
Click here for more results from Plasmodium berghei midgut invasion stage comparisons (Vlachou et al., 2005)
Ivermectin-containing blood meals at different ages (Seaman et al., 2015)
RNA-Seq experiment info
Plots and data
0.62
ANOVA
Age and growth condition and compound
Non-significant differential expression
↑ 2 days:Non-blood-fed:control
↓ 2 days:blood-fed:control
Larval salivary glands (Neira Oviedo et al., 2009)
Microarray experiment info
Plots and data
0.81
ANOVA
Organism part
Non-significant differential expression
↑ salivary gland
↓ whole_organism
Adult female tissues (Koutsos et al., 2007)
Microarray experiment info
Plots and data
0.87
ANOVA
Organism part
Non-significant differential expression
↑ midgut
↓ ovaries
Embryonic serosa (Goltsev et al., 2009)
Microarray experiment info
Plots and data
0.89
ANOVA
Organism part
Non-significant differential expression
↑ embryonic serosa
↓ embryo
Plasmodium berghei midgut invasion time-series (Vlachou et al., 2005)
Microarray experiment info
Plots and data
0.94
t-test
Disease state and disease staging
Non-significant 1.0-fold down-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:after midgut invasion
Click here for more results from Plasmodium berghei midgut invasion time-series (Vlachou et al., 2005)
Circadian rhythm: bodies, light-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
0.95
ANOVA
Time
Non-significant differential expression
↑ 52.0 h
↓ 20.0 h