Experiment |
P-value |
Test |
Experimental factor |
Summary |
Blood meal time series (Marinotti et al., 2006)
Microarray experiment info
Plots and data
|
4.7e-10 |
ANOVA |
Growth condition
|
|
|
Significant differential expression ↑ blood-fed 96h ↓ blood-fed 3h
|
|
0.00012 |
Neighbour t-test |
Growth condition
|
|
|
Significant 1.2-fold upward change between: ← blood-fed 24h → blood_fed 48h
|
|
0.0056 |
Neighbour t-test |
Growth condition
|
|
|
Significant 1.1-fold upward change between: ← blood-fed 3h → blood-fed 24h
|
|
0.0060 |
Neighbour t-test |
Growth condition
|
|
|
Significant 1.3-fold downward change between: ← Non-blood-fed → blood-fed 3h
|
|
0.010 |
Neighbour t-test |
Growth condition
|
|
|
Significant 1.1-fold upward change between: ← blood_fed 72h → blood-fed 96h
|
|
0.015 |
Neighbour t-test |
Growth condition
|
|
|
Significant 1.1-fold downward change between: ← blood_fed 48h → blood_fed 72h
|
|
0.082 |
Neighbour t-test |
Growth condition
|
|
|
Non-significant 1.1-fold downward change between: ← blood-fed 96h → blood-fed 15d
|
 Click here for more results from Blood meal time series (Marinotti et al., 2006)  |
Adult tissues (Baker et al., 2011)
Microarray experiment info
Plots and data
|
1.6e-05 |
ANOVA |
Organism part and sex
|

|
|
Significant differential expression ↑ male accessory gland:male ↓ whole body:female
|
Developmental series (Koutsos et al., 2007)
Microarray experiment info
Plots and data
|
8.8e-05 |
ANOVA |
Developmental stage and age
|

|
|
Significant differential expression ↑ adult:312 hours ↓ larva:144 hours
|
|
0.026 |
Neighbour t-test |
Developmental stage and age
|

|
|
Significant 1.3-fold downward change between: ← embryo:12-14 hours → larva:48 hours
|
|
0.030 |
Neighbour t-test |
Developmental stage and age
|

|
|
Significant 1.4-fold upward change between: ← pupa:240 hours → adult:312 hours
|
|
0.031 |
Neighbour t-test |
Developmental stage and age
|

|
|
Significant 1.3-fold downward change between: ← larva:96 hours → larva:144 hours
|
|
0.048 |
Neighbour t-test |
Developmental stage and age
|

|
|
Significant 1.5-fold upward change between: ← larva:144 hours → larva:192 hours
|
|
0.061 |
Neighbour t-test |
Developmental stage and age
|

|
|
Non-significant 1.2-fold upward change between: ← larva:48 hours → larva:96 hours
|
|
0.25 |
Neighbour t-test |
Developmental stage and age
|

|
|
Non-significant 1.3-fold upward change between: ← larva:240 hours → pupa:240 hours
|
|
0.33 |
Neighbour t-test |
Developmental stage and age
|

|
|
Non-significant 1.2-fold downward change between: ← larva:192 hours → larva:240 hours
|
 Click here for more results from Developmental series (Koutsos et al., 2007)  |
Blood-fed adult female tissues (Marinotti et al., 2006)
Microarray experiment info
Plots and data
|
0.00010 |
ANOVA |
Organism part
|
|
|
Significant differential expression ↑ midgut ↓ ovaries
|
Desiccation stress (Wang et al., 2011)
Microarray experiment info
Plots and data
|
0.00022 |
ANOVA |
Growth condition
|
|
|
Significant differential expression ↑ Exposed to 30% RH 36hr ↓ No desiccation stress
|
Larval and adult stages (Marinotti et al., 2006)
Microarray experiment info
Plots and data
|
0.00030 |
ANOVA |
Developmental stage
|
|
|
Significant differential expression ↑ adult ↓ larva
|
Multi-insecticide resistant VK population (Kwiatkowska et al., 2013)
Microarray experiment info
Plots and data
|
0.00035 |
t-test |
Strain or line
|
|
|
Significant 1.1-fold up-regulation with respect to VK v Ngousso
|
Plasmodium berghei midgut invasion stage comparisons (Vlachou et al., 2005)
Microarray experiment info
Plots and data
|
0.0010 |
t-test |
Disease state and disease staging
|

|
|
Significant 2.4-fold up-regulation with respect to invasion-deficient parasite infection:during midgut invasion v before midgut invasion
|
|
0.0087 |
t-test |
Disease state and disease staging
|

|
|
Significant 1.4-fold up-regulation with respect to wild-type parasite infection:during midgut invasion v before midgut invasion
|
|
0.022 |
t-test |
Disease state and disease staging
|

|
|
Significant 1.6-fold down-regulation with respect to invasion-deficient parasite infection:after midgut invasion v during midgut invasion
|
|
0.83 |
t-test |
Disease state and disease staging
|

|
|
Non-significant 1.0-fold down-regulation with respect to wild-type parasite infection:after midgut invasion v during midgut invasion
|
 Click here for more results from Plasmodium berghei midgut invasion stage comparisons (Vlachou et al., 2005)  |
Blood meal after 15 days (Marinotti et al., 2006)
Microarray experiment info
Plots and data
|
0.0017 |
ANOVA |
Growth condition
|
|
|
Significant differential expression ↑ Non-blood-fed 18d ↓ blood-fed 15d
|
Response to thermal stress in 2La and 2L+(a) karyotype mosquitoes (Cassone et al., 2011)
Microarray experiment info
Plots and data
|
0.0024 |
ANOVA |
Genotype and growth condition and time
|
 
|
|
Significant differential expression ↑ 2La inverted:heat-shocked:0.25 h ↓ 2La standard:heat-shocked:0.25 h
|
Two consecutive blood meals (Marinotti et al., 2006)
Microarray experiment info
Plots and data
|
0.0044 |
Neighbour t-test |
Growth condition
|
|
|
Significant 1.2-fold downward change between: ← Non-blood-fed → blood-fed 24h
|
|
0.0045 |
ANOVA |
Growth condition
|
|
|
Significant differential expression ↑ blood-fed twice ↓ blood-fed 24h
|
|
0.031 |
Neighbour t-test |
Growth condition
|
|
|
Significant 1.2-fold upward change between: ← blood-fed 24h → blood-fed twice
|
 Click here for more results from Two consecutive blood meals (Marinotti et al., 2006)  |
Plasmodium berghei midgut invasion time-series (Vlachou et al., 2005)
Microarray experiment info
Plots and data
|
0.012 |
t-test |
Disease state and disease staging
|

|
|
Significant 1.6-fold down-regulation with respect to wild-type parasite infection v invasion-deficient parasite infection:during midgut invasion
|
|
0.21 |
t-test |
Disease state and disease staging
|

|
|
Non-significant 1.2-fold down-regulation with respect to wild-type parasite infection v invasion-deficient parasite infection:before midgut invasion
|
|
0.61 |
t-test |
Disease state and disease staging
|

|
|
Non-significant 1.0-fold down-regulation with respect to wild-type parasite infection v invasion-deficient parasite infection:after midgut invasion
|
 Click here for more results from Plasmodium berghei midgut invasion time-series (Vlachou et al., 2005)  |
Female lower reproductive tract post-mating time-series (Gabrieli et al., 2014)
Microarray experiment info
Plots and data
|
0.013 |
ANOVA |
Developmental stage and growth condition
|

|
|
Significant differential expression ↑ mated adult:24 hours post-mating ↓ mated adult:3 hours post-mating
|
|
0.018 |
ANOVA |
Growth condition
|
|
|
Significant differential expression ↑ 24 hours post-mating ↓ 3 hours post-mating
|
|
0.44 |
ANOVA |
Developmental stage
|
|
|
Non-significant differential expression ↑ mated adult ↓ virgin adult
|
 Click here for more results from Female lower reproductive tract post-mating time-series (Gabrieli et al., 2014)  |
Larval salivary glands (Neira Oviedo et al., 2009)
Microarray experiment info
Plots and data
|
0.028 |
ANOVA |
Organism part
|
|
|
Significant differential expression ↑ salivary gland ↓ whole_organism
|
Mated females (Rogers et al., 2009)
Microarray experiment info
Plots and data
|
0.029 |
ANOVA |
Growth condition
|
|
|
Significant differential expression ↑ virgin 0h ↓ mated 6h
|
|
0.070 |
Neighbour t-test |
Growth condition
|
|
|
Non-significant 1.3-fold upward change between: ← mated 6h → mated 24h
|
|
0.086 |
Neighbour t-test |
Growth condition
|
|
|
Non-significant 1.2-fold downward change between: ← virgin 0h → mated 2h
|
|
0.58 |
Neighbour t-test |
Growth condition
|
|
|
Non-significant 1.1-fold downward change between: ← mated 2h → mated 6h
|
 Click here for more results from Mated females (Rogers et al., 2009)  |
DDT resistant field isolates (Tene et al, 2013)
Microarray experiment info
Plots and data
|
0.029 |
t-test |
Genotype and strain or line
|

|
|
Significant 1.1-fold up-regulation with respect to M form:Gare v Ngousso
|
|
0.066 |
t-test |
Genotype and strain or line
|

|
|
Non-significant 1.3-fold up-regulation with respect to S form:Nkolondom v Kisumu
|
|
0.13 |
ANOVA |
Genotype and strain or line
|

|
|
Non-significant differential expression ↑ S form:Nkolondom v Kisumu ↓ M form:Messa v Ngousso
|
|
0.52 |
t-test |
Genotype and strain or line
|

|
|
Non-significant 1.1-fold up-regulation with respect to M form:Messa v Ngousso
|
 Click here for more results from DDT resistant field isolates (Tene et al, 2013)  |
Adult male mosquito ageing (Cook & Sinkins, 2010)
Microarray experiment info
Plots and data
|
0.041 |
Neighbour t-test |
Age
|
|
|
Significant 1.1-fold upward change between: ← 20 days → 30 days
|
|
0.077 |
ANOVA |
Age
|
|
|
Non-significant differential expression ↑ 0 days ↓ 20 days
|
|
0.28 |
Neighbour t-test |
Age
|
|
|
Non-significant 2.2-fold downward change between: ← 0 days → 10 days
|
|
0.80 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold downward change between: ← 10 days → 20 days
|
 Click here for more results from Adult male mosquito ageing (Cook & Sinkins, 2010)  |
Circadian rhythm: heads, dark-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
|
0.056 |
ANOVA |
Time
|
|
|
Non-significant differential expression ↑ 32.0 h ↓ 0.0 h
|
Female lower reproductive tract 20E injection (Gabrieli et al., 2014)
Microarray experiment info
Plots and data
|
0.058 |
t-test |
Compound and organism part
|

|
|
Non-significant 1.2-fold up-regulation with respect to 20-hydroxyecdysone v 10% Ethanol:Spermatheca
|
|
0.75 |
t-test |
Compound and organism part
|

|
|
Non-significant 1.0-fold down-regulation with respect to 20-hydroxyecdysone v 10% Ethanol:Atrium
|
 Click here for more results from Female lower reproductive tract 20E injection (Gabrieli et al., 2014)  |
Mated vs virgin spermatheca (Shaw et al., 2014)
Microarray experiment info
Plots and data
|
0.069 |
t-test |
Developmental stage
|
|
|
Non-significant 1.3-fold up-regulation with respect to mated adult v virgin adult
|
Circadian rhythm: bodies, light-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
|
0.077 |
ANOVA |
Time
|
|
|
Non-significant differential expression ↑ 16.0 h ↓ 52.0 h
|
Hemolymph, carcass and head (Pinto et al., 2009)
Microarray experiment info
Plots and data
|
0.11 |
ANOVA |
Organism part
|
|
|
Non-significant differential expression ↑ head ↓ hemolymph
|
Male vs. female (Marinotti et al., 2006)
Microarray experiment info
Plots and data
|
0.12 |
ANOVA |
Sex
|
|
|
Non-significant differential expression ↑ male ↓ female
|
Insecticide resistance in the salivary glands (Isaacs et al., 2018)
Microarray experiment info
Plots and data
|
0.13 |
t-test |
Genotype and strain or line
|

|
|
Non-significant 1.2-fold down-regulation with respect to resistant v unexposed:Kihihi
|
|
0.29 |
t-test |
Genotype and strain or line
|

|
|
Non-significant 1.1-fold down-regulation with respect to resistant v unexposed:Nagongera
|
|
0.73 |
ANOVA |
Genotype and strain or line
|

|
|
Non-significant differential expression ↑ resistant v unexposed:Nagongera ↓ resistant v unexposed:Kihihi
|
 Click here for more results from Insecticide resistance in the salivary glands (Isaacs et al., 2018)  |
Plasmodium berghei infected vs. uninfected (Zhao et al., 2012)
Microarray experiment info
Plots and data
|
0.15 |
Neighbour t-test |
Disease state and disease staging
|

|
|
Non-significant 1.2-fold downward change between: ← P. berghei NK65 infected v uninfected:10 days post infection → P. berghei NK65 infected v uninfected:17 days post infection
|
|
0.17 |
t-test |
Disease state and disease staging
|

|
|
Non-significant 1.2-fold up-regulation with respect to P. berghei NK65 infected v uninfected:10 days post infection
|
|
0.73 |
t-test |
Disease state and disease staging
|

|
|
Non-significant 1.0-fold down-regulation with respect to P. berghei NK65 infected v uninfected:17 days post infection
|
 Click here for more results from Plasmodium berghei infected vs. uninfected (Zhao et al., 2012)  |
Embryonic development (Goltsev et al., 2009)
Microarray experiment info
Plots and data
|
0.16 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold upward change between: ← 19h → 22h
|
|
0.18 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold downward change between: ← 16h → 19h
|
|
0.19 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.2-fold upward change between: ← 2h → 4h
|
|
0.25 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold downward change between: ← 28.5h → 31h
|
|
0.31 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold downward change between: ← 6h → 7h
|
|
0.45 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold upward change between: ← 40h → 43h
|
|
0.47 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold downward change between: ← 4h → 6h
|
|
0.49 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold downward change between: ← 43h → 46h
|
|
0.52 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.0-fold upward change between: ← 13h → 16h
|
|
0.56 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold downward change between: ← 37h → 40h
|
|
0.58 |
ANOVA |
Age
|
|
|
Non-significant differential expression ↑ 4h ↓ 19h
|
|
0.70 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold upward change between: ← 34h → 37h
|
|
0.77 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.0-fold downward change between: ← 8h → 10h
|
|
0.91 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.0-fold downward change between: ← 10h → 13h
|
|
0.91 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.0-fold downward change between: ← 25h → 28.5h
|
|
0.92 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.0-fold upward change between: ← 31h → 34h
|
|
0.94 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.0-fold downward change between: ← 22h → 25h
|
|
0.98 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.0-fold upward change between: ← 7h → 8h
|
 Click here for more results from Embryonic development (Goltsev et al., 2009)  |
Adult female mosquito ageing (Cook & Sinkins, 2010)
Microarray experiment info
Plots and data
|
0.17 |
ANOVA |
Age
|
|
|
Non-significant differential expression ↑ 0 days ↓ 30 days
|
|
0.36 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.2-fold downward change between: ← 0 days → 10 days
|
|
0.49 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.2-fold downward change between: ← 10 days → 20 days
|
|
0.81 |
Neighbour t-test |
Age
|
|
|
Non-significant 1.1-fold downward change between: ← 20 days → 30 days
|
 Click here for more results from Adult female mosquito ageing (Cook & Sinkins, 2010)  |
Circadian rhythm: heads, light-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
|
0.17 |
ANOVA |
Time
|
|
|
Non-significant differential expression ↑ 60.0 h ↓ 16.0 h
|
Male vs. female (Koutsos et al., 2007)
Microarray experiment info
Plots and data
|
0.17 |
ANOVA |
Sex
|
|
|
Non-significant differential expression ↑ male ↓ female
|
Embryonic serosa (Goltsev et al., 2009)
Microarray experiment info
Plots and data
|
0.17 |
ANOVA |
Organism part
|
|
|
Non-significant differential expression ↑ embryonic serosa ↓ embryo
|
Alimentary canal compartments (Neira Oviedo et al., 2008)
Microarray experiment info
Plots and data
|
0.21 |
ANOVA |
Organism part
|
|
|
Non-significant differential expression ↑ hindgut ↓ gastric caeca
|
Chloroquine exposure (Abrantes et al., 2008)
Microarray experiment info
Plots and data
|
0.24 |
t-test |
Compound and disease state
|

|
|
Non-significant 1.1-fold up-regulation with respect to chloroquine v none:uninfected
|
|
0.58 |
t-test |
Compound and disease state
|

|
|
Non-significant 1.1-fold down-regulation with respect to chloroquine v none:Plasmodium berghei infected
|
 Click here for more results from Chloroquine exposure (Abrantes et al., 2008)  |
M and S form gravid females (Cassone et al., 2008)
Microarray experiment info
Plots and data
|
0.26 |
ANOVA |
Genotype
|
|
|
Non-significant differential expression ↑ M form ↓ S form
|
|
0.53 |
ANOVA |
Genotype and strain or line
|

|
|
Non-significant differential expression ↑ M form:Mali-NIH ↓ S form:Pimperena
|
 Click here for more results from M and S form gravid females (Cassone et al., 2008)  |
M and S form virgin females (Cassone et al., 2008)
Microarray experiment info
Plots and data
|
0.31 |
ANOVA |
Genotype and strain or line
|

|
|
Non-significant differential expression ↑ M form:M-GA-CAM ↓ M form:Mali-NIH
|
|
0.71 |
ANOVA |
Genotype
|
|
|
Non-significant differential expression ↑ S form ↓ M form
|
 Click here for more results from M and S form virgin females (Cassone et al., 2008)  |
M and S form 4th instar larvae (Cassone et al., 2008)
Microarray experiment info
Plots and data
|
0.37 |
ANOVA |
Genotype and strain or line
|

|
|
Non-significant differential expression ↑ M form:M-GA-CAM ↓ S form:Pimperena
|
|
0.37 |
ANOVA |
Genotype
|
|
|
Non-significant differential expression ↑ M form ↓ S form
|
 Click here for more results from M and S form 4th instar larvae (Cassone et al., 2008)  |
Resistant vs susceptible isofemales from Tororo (Wilding et al., 2014)
Microarray experiment info
Plots and data
|
0.38 |
t-test |
Genotype
|
|
|
Non-significant 1.0-fold up-regulation with respect to resistant v susceptible
|
Adult female tissues (Koutsos et al., 2007)
Microarray experiment info
Plots and data
|
0.63 |
ANOVA |
Organism part
|
|
|
Non-significant differential expression ↑ ovaries ↓ midgut
|
Circadian rhythm: bodies, dark-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
|
0.88 |
ANOVA |
Time
|
|
|
Non-significant differential expression ↑ 32.0 h ↓ 20.0 h
|
Hemocyte response to Plasmodium berghei infection (Pinto et al., 2009)
Microarray experiment info
Plots and data
|
0.91 |
Neighbour t-test |
Disease state
|
|
|
Non-significant 1.0-fold downward change between: ← invasion-deficient parasite infection → wild-type parasite infection
|