Bioinformatics Resource for Invertebrate Vectors of Human Pathogens
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Gene AGAP011294 Expression Report
Gene links
Anopheles gambiae

Probe Information show details
Expression summary
Experiment P-value Test Experimental factor Summary
Circadian rhythm: heads, dark-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
7.4e-15
ANOVA
Time
Significant differential expression
↑ 16.0 h
↓ 24.0 h
Circadian rhythm: heads, light-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
6.3e-13
ANOVA
Time
Significant differential expression
↑ 36.0 h
↓ 16.0 h
Adult tissues (Baker et al., 2011)
Microarray experiment info
Plots and data
9.8e-13
ANOVA
Organism part and sex
Significant differential expression
↑ midgut:male
↓ ovaries:female
MR4 cell-lines (AVCL consortium, 2014)
RNA-Seq experiment info
Plots and data
1.5e-11
ANOVA
Strain or line
Significant differential expression
↑ MRA-920 L35
↓ MRA-918 4a-3A
Circadian rhythm: bodies, light-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
2.2e-10
ANOVA
Time
Significant differential expression
↑ 32.0 h
↓ 16.0 h
Response to thermal stress in 2La and 2L+(a) karyotype mosquitoes (Cassone et al., 2011)
Microarray experiment info
Plots and data
1.4e-09
ANOVA
Genotype and growth condition and time
Significant differential expression
↑ 2La inverted:heat-shocked:8.0 h
↓ 2La inverted:heat-shocked:0.25 h
Developmental series (Koutsos et al., 2007)
Microarray experiment info
Plots and data
5.5e-08
ANOVA
Developmental stage and age
Significant differential expression
↑ adult:312 hours
↓ larva:96 hours
Click here for more results from Developmental series (Koutsos et al., 2007)
Blood meal time series (Marinotti et al., 2006)
Microarray experiment info
Plots and data
1.1e-07
ANOVA
Growth condition
Significant differential expression
↑ blood-fed 15d
↓ blood-fed 3h
Click here for more results from Blood meal time series (Marinotti et al., 2006)
Blood-fed adult female tissues (Marinotti et al., 2006)
Microarray experiment info
Plots and data
3.3e-06
ANOVA
Organism part
Significant differential expression
↑ midgut
↓ ovaries
Circadian rhythm: bodies, dark-dark (Rund et al., 2011)
Microarray experiment info
Plots and data
5.0e-06
ANOVA
Time
Significant differential expression
↑ 16.0 h
↓ 44.0 h
Sua5B cell-line infected vs uninfected (AVCL consortium, 2014)
RNA-Seq experiment info
Plots and data
0.00018
ANOVA
Disease state
Significant differential expression
↑ Uninfected
↓ wAlB infected
Female lower reproductive tract post-mating time-series (Gabrieli et al., 2014)
Microarray experiment info
Plots and data
0.00018
ANOVA
Developmental stage and growth condition
Significant differential expression
↑ mated adult:24 hours post-mating
↓ virgin adult:12 hours post-mating
Click here for more results from Female lower reproductive tract post-mating time-series (Gabrieli et al., 2014)
Desiccation stress (Wang et al., 2011)
Microarray experiment info
Plots and data
0.00021
ANOVA
Growth condition
Significant differential expression
↑ No desiccation stress
↓ Exposed to 30% RH 36hr
MOS55 cell-line infected vs uninfected (AVCL consortium, 2014)
RNA-Seq experiment info
Plots and data
0.00025
ANOVA
Disease state
Significant differential expression
↑ wMel infected
↓ wMelPop infected
Plasmodium berghei infections (Mendes et al., 2011)
Microarray experiment info
Plots and data
0.0011
ANOVA
Disease state and disease staging
Significant differential expression
↑ low-intensity Plasmodium berghei infected v heat-inactivated mock infected:during midgut invasion
↓ low-intensity Plasmodium berghei infected v heat-inactivated mock infected:after midgut invasion
Click here for more results from Plasmodium berghei infections (Mendes et al., 2011)
Plasmodium falciparum infections (Mendes et al., 2011)
Microarray experiment info
Plots and data
0.0011
t-test
Disease state
Significant 1.6-fold down-regulation with respect to
high-intensity Plasmodium falciparum infected v heat-inactivated mock infected
Click here for more results from Plasmodium falciparum infections (Mendes et al., 2011)
Sex-biased expression in gambiae (Papa et al., 2017)
RNA-Seq experiment info
Plots and data
0.0012
ANOVA
Organism part and sex
Significant differential expression
↑ carcass:female
↓ reproductive tissues:male
M and S form gravid females (Cassone et al., 2008)
Microarray experiment info
Plots and data
0.0029
ANOVA
Genotype
Significant differential expression
↑ M form
↓ S form
Click here for more results from M and S form gravid females (Cassone et al., 2008)
Hemocyte response to Plasmodium berghei infection (Pinto et al., 2009)
Microarray experiment info
Plots and data
0.0035
Neighbour t-test
Disease state
Significant 4.0-fold upward change between:
← invasion-deficient parasite infection
→ wild-type parasite infection
Male vs. female (Marinotti et al., 2006)
Microarray experiment info
Plots and data
0.0045
ANOVA
Sex
Significant differential expression
↑ male
↓ female
Hemolymph, carcass and head (Pinto et al., 2009)
Microarray experiment info
Plots and data
0.010
ANOVA
Organism part
Significant differential expression
↑ hemolymph
↓ head
Ivermectin-containing blood meals at different ages (Seaman et al., 2015)
RNA-Seq experiment info
Plots and data
0.014
ANOVA
Age and growth condition and compound
Significant differential expression
↑ 2 days:Non-blood-fed:control
↓ 6 days:blood-fed twice:ivermectin
Male vs. female (Koutsos et al., 2007)
Microarray experiment info
Plots and data
0.017
ANOVA
Sex
Significant differential expression
↑ male
↓ female
DDT resistant field isolates (Tene et al, 2013)
Microarray experiment info
Plots and data
0.021
t-test
Genotype and strain or line
Significant 1.7-fold down-regulation with respect to
S form:Nkolondom v Kisumu
Click here for more results from DDT resistant field isolates (Tene et al, 2013)
Multi-insecticide resistant VK population (Kwiatkowska et al., 2013)
Microarray experiment info
Plots and data
0.022
t-test
Strain or line
Significant 1.4-fold up-regulation with respect to
VK v Ngousso
Sex-bias during development (Magnusson et al., 2011)
Microarray experiment info
Plots and data
0.030
t-test
Developmental stage and age and sex
Significant 1.2-fold down-regulation with respect to
larva:96 hours:female v male
Click here for more results from Sex-bias during development (Magnusson et al., 2011)
Plasmodium berghei midgut invasion stage comparisons (Vlachou et al., 2005)
Microarray experiment info
Plots and data
0.035
t-test
Disease state and disease staging
Significant 1.4-fold up-regulation with respect to
invasion-deficient parasite infection:during midgut invasion v before midgut invasion
Click here for more results from Plasmodium berghei midgut invasion stage comparisons (Vlachou et al., 2005)
Blood meal after 15 days (Marinotti et al., 2006)
Microarray experiment info
Plots and data
0.051
ANOVA
Growth condition
Non-significant differential expression
↑ Non-blood-fed 18d
↓ blood-fed 15d
Alimentary canal compartments (Neira Oviedo et al., 2008)
Microarray experiment info
Plots and data
0.053
ANOVA
Organism part
Non-significant differential expression
↑ gastric caeca
↓ posterior midgut
M and S form virgin females (Cassone et al., 2008)
Microarray experiment info
Plots and data
0.071
ANOVA
Genotype and strain or line
Non-significant differential expression
↑ M form:M-GA-CAM
↓ M form:Mali-NIH
Click here for more results from M and S form virgin females (Cassone et al., 2008)
Embryonic development (Goltsev et al., 2009)
Microarray experiment info
Plots and data
0.079
Neighbour t-test
Age
Non-significant 1.1-fold downward change between:
← 10h
→ 13h
Click here for more results from Embryonic development (Goltsev et al., 2009)
Plasmodium berghei midgut invasion time-series (Vlachou et al., 2005)
Microarray experiment info
Plots and data
0.11
t-test
Disease state and disease staging
Non-significant 1.5-fold down-regulation with respect to
wild-type parasite infection v invasion-deficient parasite infection:during midgut invasion
Click here for more results from Plasmodium berghei midgut invasion time-series (Vlachou et al., 2005)
Mated females (Rogers et al., 2009)
Microarray experiment info
Plots and data
0.12
Neighbour t-test
Growth condition
Non-significant 1.2-fold downward change between:
← mated 2h
→ mated 6h
Click here for more results from Mated females (Rogers et al., 2009)
Female lower reproductive tract 20E injection (Gabrieli et al., 2014)
Microarray experiment info
Plots and data
0.13
t-test
Compound and organism part
Non-significant 1.8-fold down-regulation with respect to
20-hydroxyecdysone v 10% Ethanol:Atrium
Click here for more results from Female lower reproductive tract 20E injection (Gabrieli et al., 2014)
Resistant vs susceptible isofemales from Tororo (Wilding et al., 2014)
Microarray experiment info
Plots and data
0.15
t-test
Genotype
Non-significant 1.1-fold down-regulation with respect to
resistant v susceptible
Adult female mosquito ageing (Cook & Sinkins, 2010)
Microarray experiment info
Plots and data
0.31
Neighbour t-test
Age
Non-significant 1.6-fold downward change between:
← 20 days
→ 30 days
Click here for more results from Adult female mosquito ageing (Cook & Sinkins, 2010)
Insecticide resistance in the salivary glands (Isaacs et al., 2018)
Microarray experiment info
Plots and data
0.38
t-test
Genotype and strain or line
Non-significant 1.1-fold up-regulation with respect to
resistant v unexposed:Kihihi
Click here for more results from Insecticide resistance in the salivary glands (Isaacs et al., 2018)
Two consecutive blood meals (Marinotti et al., 2006)
Microarray experiment info
Plots and data
0.38
Neighbour t-test
Growth condition
Non-significant 1.1-fold downward change between:
← Non-blood-fed
→ blood-fed 24h
Click here for more results from Two consecutive blood meals (Marinotti et al., 2006)
Adult female tissues (Koutsos et al., 2007)
Microarray experiment info
Plots and data
0.43
ANOVA
Organism part
Non-significant differential expression
↑ midgut
↓ ovaries
Larval and adult stages (Marinotti et al., 2006)
Microarray experiment info
Plots and data
0.52
ANOVA
Developmental stage
Non-significant differential expression
↑ adult
↓ larva
Plasmodium berghei infected vs. uninfected (Zhao et al., 2012)
Microarray experiment info
Plots and data
0.54
t-test
Disease state and disease staging
Non-significant 1.2-fold up-regulation with respect to
P. berghei NK65 infected v uninfected:10 days post infection
Click here for more results from Plasmodium berghei infected vs. uninfected (Zhao et al., 2012)
Embryonic serosa (Goltsev et al., 2009)
Microarray experiment info
Plots and data
0.59
ANOVA
Organism part
Non-significant differential expression
↑ embryo
↓ embryonic serosa
Modulation of blood seeking, feeding & susceptibility to infection (Emami et al., 2017)
RNA-Seq experiment info
Plots and data
0.62
ANOVA
Growth condition and time
Non-significant differential expression
↑ blood-fed with HMBPP:3.0 h
↓ blood-fed:3.0 h
Translational regulation in the midgut during falciparum infection (Mead et al., 2012)
RNA-Seq experiment info
Plots and data
0.65
ANOVA
Material type and disease state
Non-significant differential expression
↑ total RNA:uninfected control
↓ non-polysome associated RNA:uninfected control
Chloroquine exposure (Abrantes et al., 2008)
Microarray experiment info
Plots and data
0.66
t-test
Compound and disease state
Non-significant 1.1-fold up-regulation with respect to
chloroquine v none:Plasmodium berghei infected
Click here for more results from Chloroquine exposure (Abrantes et al., 2008)
Mated vs virgin spermatheca (Shaw et al., 2014)
Microarray experiment info
Plots and data
0.69
t-test
Developmental stage
Non-significant 1.2-fold up-regulation with respect to
mated adult v virgin adult
Adult male mosquito ageing (Cook & Sinkins, 2010)
Microarray experiment info
Plots and data
0.71
Neighbour t-test
Age
Non-significant 1.9-fold upward change between:
← 10 days
→ 20 days
Click here for more results from Adult male mosquito ageing (Cook & Sinkins, 2010)
M and S form 4th instar larvae (Cassone et al., 2008)
Microarray experiment info
Plots and data
0.75
ANOVA
Genotype
Non-significant differential expression
↑ M form
↓ S form
Click here for more results from M and S form 4th instar larvae (Cassone et al., 2008)
Larval salivary glands (Neira Oviedo et al., 2009)
Microarray experiment info
Plots and data
0.86
ANOVA
Organism part
Non-significant differential expression
↑ salivary gland
↓ whole_organism
Transcript abundance after bloodmeal (Vannini et al., 2014)
RNA-Seq experiment info
Plots and data
0.94
ANOVA
Growth condition
Non-significant differential expression
↑ Non-blood-fed
↓ blood-fed