Why do you reanalyze the microarray and RNAseq data?


We have developed (and are always looking at improving) a standardised analysis pipeline for microarray expression data in VectorBase. We use this in preference to the original authors' processed data for the following reasons:

  • we have a complete audit trail from raw data to final p-value
  • we can repeat/refine the analysis whenever we want.
  • data entry/curation is simplified
  • the authors' processed data is nearly always available from either
    • the publication's supplementary information
    • ArrayExpress
    • GEO
    • the authors