DWGA (Derived from Whole Genome Alignments)

Human versus Chimpanzee exception: The human versus chimpanzee orthologue predictions were obtained in a completely different manner. Since the current chimpanzee genome sequence assembly is the result of low-coverage sequencing, the assembled sequence is of too poor quality to generate a gene set on the classical Ensembl gene build pipeline. The chimpanzee gene set produced by Ensembl has rather been generated by "projecting" human genes to the chimpanzee genome through whole genome BLASTz alignments between both species and filtering for orthologue sequence alignments. The result of this procedure is de facto the human - chimpanzee orthologue set that has been Derived from Whole Genome Alignments (DWGA). See the Prediction Method section on a relevant Ensembl Gene Report page.

There is currently no content classified with this term.

Subscribe to RSS - DWGA (Derived from Whole Genome Alignments)