YAC (Yeast Artificial Chromosome)

Originated from a bacterial plasmid, a YAC contains a yeast centromeric region (CEN), a yeast origin of DNA replication, a cluster of unique rectriction sites and a selectable marker and a telomere region at the en of each arm. YACs are capable of cloning extremely large segments of DNA (over 1 megabase long) into a host cell, where the DNA is propagated along with the other chromosomes of the yeast cell.

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