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Newsletter 10 (Oct 2010)

  • Driving Biological Projects
    A few months ago, VectorBase invited proposals for Driving Biological Projects (DBPs), funded by NIH/NIAID, these projects should use high-throughput experimental technologies to functionally characterize the genome, proteome or metabolome of vector species.
    Two projects were selected:
    • Comparative neurotranscriptome of Aedes aegypti PDF
    • Physical reference maps for vector genome assembly PDF

    The data generated will be made available through VectorBase. The next call should be announced in about 14 months (Jan.2012).

  • Culex quinquefasciatus genome paper
    The paper relating the sequencing, annotation and analysis of the Culex quinquefasciatus genome has been published this month in Science (Arensburger et al., 2010). As well as giving an overview of the genome structure and of the gene content, it presents a comparison of the three mosquito genomes and shows that increase in Culex gene number is partially due to a gene family expansion. A companion paper (Bartholomay et al., 2010) describes Culex responses to infection by diverse pathogens, and compares these responses in the three mosquitoes.

    Newsletter 11 (May 2011)

    • Funding Opportunity
      The NIAID-funded VectorBase invites research investigations called Driving Biological Projects (DBPs) from organizations housing experimental laboratories having expertise and knowledge in working with arthropod vectors of human pathogens. We anticipate making two awards of up to $600K each by April 1, 2012. A two page Letter of Intent (LOI) is due August 1, 2011. Full proposals will be solicited by invitation only, with a deadline of November 1, 2011. See the full solicitation from the VectorBase site and send questions to
    • Anopheles Genomes Cluster
      Samples are now in sequencing at the Broad Institute for the NHGRI/NIAID-supported project, “Genome Analysis of Vectorial Capacity in Major Anopheles Vectors of Malaria Parasites”. VectorBase looks forward to working together with the Broad and members of the vector community to process and host these new genomes and their meta-data. Please visit VectorBase often for project information, updates, and data as they become available.

    Newsletter 12 (Nov 2011)

    • Genome projects approved
      VectorBase has been informed that the NIH/NIAID vector genome working group has approved two new projects. One will sequence the mite vector of scrub typhus, Leptotrombidium deliense, and provide additional genome and transcriptome sequencing of Ixodes scapularis and related ticks. The second will target genomes of 11 Simulium (black fly) species, including the major S. damnosum siblings, S. woodii, S. ochraceum and S. vittatum.

      Newsletter 13 (Sep 2012)

      New website coming soon!

      The VectorBase developers have been busy creating a new website with improved search and navigation, as well as a more consistent look and feel. During the transition period of several months, both new and old sites will run in parallel. Your feedback is very welcome at any time.

      Newsletter 14 (Feb 2014)

      Newsletter 1 (Sep 2007)

      • Launch of the Newsletter
        Welcome to the first issue of the VectorBase Newsletter. The newsletter highlights new data sets and tool developments available from VectorBase as well as giving advanced notice of upcoming changes. The newsletter will be sent quarterly to those subscribed to the mail list.

        Newsletter 2 (Jan 2008)

        • Culex pipiens The genome of the mosquito Culex pipiens, vector of the West Nile Virus, has been sequenced and annotated and is now available at VectorBase. It complements the existing genomes of Anopheles gambiae and Aedes aegypti, completing the "mosquito triad", with one representative in each of the three main mosquito families being sequenced (Anopheline, Aedine and Culicine). The genome has been sequenced jointly by the Broad Institute and J. Craig Venter Institute (JCVI), and funded by NIAID. The shotgun sequencing was completed at the end of June 2006 and a first assembly of the 3,171 supercontigs, CpipJ1, has been produced by The Broad Institute using their whole genome assembly package ARACHNE. The 540 Mb assembly has been jointly annotated by the Broad Institute, JCVI and VectorBase. A total of 20,316 protein-coding genes were identified. Fasta files of the gene, transcript and protein sequences are available in the download section of VectorBase and the genome can be browse via our genome browser, with comparative data linking the three mosquito genomes.

        Newsletter 3 (Apr 2008)

        • Ixodes scapularis
          The genome of the blacklegged tick, a vector of Lyme disease, has been sequenced by the Broad Institute and the J. Craig Venter Institute (JCVI), and assembled by the latter into ~570,600 contigs and ~369,500 supercontigs. The assembly has an estimated 3.8X coverage of the genome and a total length of 1.8 Gb (including gaps). The contigs and supercontigs have been deposited in GenBank and are accessible at VectorBase.
        • Anopheles gambiae - M & S forms
          Two new molecular forms of Anopheles gambiae M and S, have been sequenced by the JCVI and the Washington University Genome Sequencing Center.

          Newsletter 4 (Jul 2008)

          • Taxonomic change
            NCBI have changed the taxonomic name for Culex pipiens quinquefasciatus to simply Culex quinquefasciatus. Over the coming months VectorBase will be making this change on the website in line with the GenBank entries. The taxon identifier remains unchanged (7176).

            Newsletter 5 (Nov 2008)

            • VectorBase Forum
              Following several user requests we have set up a forum for the community to post conference announcements, job offers, ask questions or just discuss vectors and their genomes. The forum is open to anyone but posting message requires registration.

              Newsletter 6 (Apr 2009)

              Newsletter 7 (Oct 2009)

              • Renewal of VectorBase funding
                VectorBase is delighted to announce that NIH-NIAID has renewed our funding, confirming that VectorBase will be around for another 5 years. Two staff members have left at the end of their contract: Martin Hammond and Kathy Campbell who will be missed and we would like to thank them for their efforts over the past 5 years.
                A big thank you to the members of the community who showed their support by sending e-mails or letters.
                Our plan for the coming years is to keep serving, and updating, the current species, but also to increase the list of organisms. We will soon be adding the genomes of Rhodnius prolixus, a triatomine vector of Chagas disease, and Glossina morsitans, the tsetse vector of sleeping sickness. Developments in new sequencing technologies will also provide insights into population structure, gene expression and improved gene predictions across all species. We welcome suggestions from the community so if you have any wishes for VectorBase, please let us know.

                Newsletter 8 (Feb 2010)

                • Driving Biological Projects solicitation
                  VectorBase invites proposals for Driving Biological Projects (DBPs) that use high-throughput experimental technologies to functionally characterize the genome, proteome or metabolome of vector species. We invite letters of intent (submission deadline 28th February 2010) with selected full proposals by 31st March. Full details are available in PDF format from the VectorBase website PDF and queries and proposals should be emailed to
                • Call for white papers
                  The Arthropod Genomics Consortium has launched a website to aid coordination between researchers with a view of writing white papers and fostering future collaborations. One recent development is the BGI proposal to sequence 1000 plant and animal genomes and they are inviting white paper submission for genomes of interest. More details are available on the arthropod genomes site or from the BGI.

                Newsletter 9 (Jul 2010)

                • Release cycle
                  Until recently, new data were added to VectorBase on an ad-hoc basis. We decided to have a regular bi-monthly release cycle, and the first release was in April this year. This release was a test, invisible to most users, and no data were changed. However, our second release has brought a big change: a new style genome browser.
                  Releases are named by the year and month of their release date, e.g. VB-2010-06. An e-mail will be sent to our mailing list with release notes describing what’s new. Unfortunately we will be unable to keep an archive site of previous releases, but you will still be able to access the data as flat files.
                • AnoEST retirement/
                  Due to the rapid influx of new data, VectorBase is no longer able to maintain the legacy AnoEST resource. It will remain available, but unsupported, for the foreseeable future. Similar functionality is available within the VectorBase genome browser.
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