sleeping sickness

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Glossina morsitans

Image: 
Glossina morsitans
Community contact: 
Serap Aksoy
Body: 

Male and female tsetse flies are the vectors of the trypanosomes that cause African sleeping sickness in humans and nagana in animals. It is conservatively estimated by the World Health Organization that there are currently between 300,000 and 500,000 cases of African sleeping sickness, with 60 million people at risk in 37 countries covering 40% of Africa. After a devastating epidemic in the early 20th century, when a million people died of sleeping sickness, the disease almost disappeared from Africa by the 1960s. However, we are now in the midst of another epidemic, with increasing numbers of new infections and mortality (55,000 deaths in 1993; 66,000 in 1999), and a disease burden of 2.05 million disability adjusted life years (DALY).

Glossina morsitans distribution is not accurately known in all countries. The subspecies G. morsitans submorsitans extends as a very large but broken belt throughout West Africa, into southern Sudan, northern Uganda.and Ethiopia. Very large belts of G. morsitans centralis occur in Zaire, Zambia, Angola, Botswana, Tanzania, Rwanda and Burundi; belts of G. morsitans morsitans occur in Tanzania, Mozambique, Zimbabwe, Zambia and Malawi. The boundary separating the two subspecies G. morsitans centralis and G. morsitans morsitans corresponds roughly with the Atlantic/Indian Ocean watershed.

The project has been jointly funded by the Wellcome Trust, WHO/TDR, RIKEN, the University of Tokyo and NIH/NIAID.

Short Name: 
gmorsitans
Organism taxonomy: 

GmorY1

The Glossina morsitans assembly was released by the Sanger Center in December 2010 and is in the process of being released. It consists of 13,807 supercontigs.

Assembly name: 
GmorY1
Release date: 
Wednesday, December 1, 2010

Yale

The Glossina morsitans Yale strain comes from a colony hosted at the Yale School of Public Health, in the Aksoy lab.

Scaffold count: 
13 807
Scaffold N50 (bp): 
120 413
GenBank WGS Accession: 
CCAG000000000
GenBank WGS Version: 
CCAG000000000.1
Assembly status: 
Current
Sequencing method: 
Sanger, 454, and Illumina
Assembly software: 
CABOG
Finishing status: 
draft
Genome Size (bp): 
366,195,856

Yale

The Glossina morsitans Yale strain comes from a colony hosted at the Yale School of Public Health, in the Aksoy lab.

Strain name: 
Yale
Sort weight: 
100
Ensembl organism name: 
Glossina_morsitans
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